GSV 1.0 (HIV genome mutual information)
This page shows mutual information estimates between every base
of the HIV genome (9032 bases in these experiments). The image is
zoomable down to single base resolution with an interface much
like Google Maps.
The information in this visualization is based on a single
sample from a single patient where we estimate there to be about
six major HIV genome-types in the sample.
PacBio long reads allow this estimate of mutual information
because we sequence almost the entire HIV genome from single
molecules in single reads. The artifacts at the lower-left and
upper-right are caused by small sample where we don't capture to
exactly the ends of the genome (caused by fewer reads at the
longest lengths as well as sample prep issues).
Mutual information measures the information above independence
assumptions. This might be caused by selection pressures
(structural, coding, ..) as HIV explores the mutation
Clicking will show what genes are annotated at those genome
positions in the text to the right of the image. geneBhit
represents the x-axis while geneEhit represents the y-axis.
1.0: http://mike.teczno.com/giant/pan/. I
have had better luck using Chrome and have seen issues in
Here is a image annotated with a subset of the gene